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Po-Hsiang Wang

Education and Research Experience

  • Apr 2025 – Oct 2025 Singapore Institute of Food and Biotechnology Innovation (SIFBI) Agency for Science, Technology and Research (A*STAR), Singapore Position: Associate Senior Professional / Associate Senior Researcher (Full-time)
  • Aug 2020 – Mar 2025 Graduate Institute of Environmental Engineering National Central University, Taiwan Position: Intermediate Professional / Researcher (Full-time)
  • Oct 2018 – Jun 2020 Earth-Life Science Institute (ELSI) Institute of Science Tokyo, Japan Position: Researcher / Full-time Staff
  • Jul 2018 – Sep 2018 Department of Chemical Engineering & Applied Chemistry University of Toronto, Canada Position: Researcher / Research Assistant (Full-time)
  • Jan 2014 – Nov 2018 University of Toronto, Canada Ph.D. in Biological Engineering
  • Jul 2010 – Jul 2011 Chang Gung University, Taiwan M.Sc. in Natural Product Chemistry
  • Sep 2006 – Jun 2010 Chang Gung University, Taiwan B.Sc. in Biomedical Sciences

Selected Publications

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    Wang, P. H., Wu, T. Y., Chen, Y. L., Gicana, R. G., Lee, T. H., Chen, M. J., Hsiao, T. H., Lu, M. Y. J., Lai, Y. L., Wang, T. Y., Li, J. Y., & Chiang, Y. R. (2025). Bacterial estrogenesis without oxygen: Wood-Ljungdahl pathway likely contributed to the emergence of estrogens in the biosphere. Proceedings of the National Academy of Sciences of the United States of America, 122(10). 

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    Ng, I. S., Wang, P.-H., Ting, W.-W., & Juo, J.-J. (2025). Recent progress in one-pot enzymatic synthesis and regeneration of high-value cofactors. Trends in Biotechnology, 43(2), 270-273. 

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    Wang, P.-H., Chen, Y.-L., Wei, S. T.-S., Wu, K., Lee, T.-H., Wu, T.-Y., & Chiang, Y.-R. (2019). Retroconversion of estrogens into androgens by bacteria via a cobalamin-mediated methylation. Proceedings of the National Academy of Sciences of the United States of America, 117(3), 1395-1403. 

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    Nishikawa, S., Yu, W. C., Chiang, Y. R., Wu, T. Y., Tang, Khusnutdinova, A., Yakunin, A., Fujishima, K., & Wang, P. H. (2025). Methanol-Driven, One-Pot Chemoenzymatic-Adenosylmethionine Regeneration for Ambient Cobalamin-Dependent Methyltransferase Reactions. ACS Catalysis, 15(15), 13689-13703. 

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    Wang, K. C., Nishikawa, S., Ting, W. W., Luo, X. H., Takahashi, T., Jia, T. Z., Huang, M. H., Fujishima, K., Ng, I. S., & Wang, P. H. (2025). Sustainable chemo-enzymatic NADP(H) synthesis from biomass-derived xylose, polyphosphate, and nicotinamide. Green Chemistry, 27(22), 6437-6448. 

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    Nishikawa, S., Yu, W. C., Jia, T. Z., He, M. J., Khusnutdinova, A., Yakunin, A. F., Chiang, Y. R., Fujishima, K., & Wang, P. H. (2024). Amino Acid Self-Regenerating Cell-Free Protein Synthesis System that Feeds on PLA Plastics, CO, Ammonium, and α-Ketoglutarate. ACS Catalysis, 14(10), 7696-7706. 

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    Lin, Y. H., Nishikawa, S., Jia, T. Z., Yeh, F. I., Khusnutdinova, A., Yakunin, A. F., Fujishima, K., & Wang, P. H. (2023). One-pot chemo-enzymatic synthesis and one-step recovery of length-variable long-chain polyphosphates from microalgal biomass. Green Chemistry, 25(23), 9896-9907. 

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    Wang, P. H., Nishikawa, S., McGlynn, S. E., & Fujishima, K. (2023). One-Pot Synthesis of [4Fe-4S] Proteins Using a Recombinant SUF System under Aerobic Conditions. ACS Synthetic Biology, 12(10), 2887-2896. 

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    Wang, P. H., Khusnutdinova, A. N., Luo, F., Xiao, J., Nemr, K., Flick, R., Brown, G., Mahadevan, R., Edwards, E. A., & Yakunin, A. F. (2018). Biosynthesis and Activity of Prenylated FMN Cofactors. Cell Chemical Biology, 25(5), 560-+. 

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    Yan, J., Bi, M., Bourdon, A. K., Farmer, A. T., Wang, P.-H., Molenda, O., Quaile, A. T., Jiang, N., Yang, Y., Yin, Y., Şimşir, B., Campagna, S. R., Edwards, E. A., & Löffler, F. E. (2017). Purinyl-cobamide is a native prosthetic group of reductive dehalogenases. Nature Chemical Biology, 14(1), 8-14.

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Academic Rewards

  • (1) Minxuan Huang and Po-Hsiang Wang. "Upcycling soybean pulp for sustainable amino acid and subsequent protein biomanufacturing via a one-pot thermophilic protease cascade treatment." 2023 SDGs Academic Paper Award - Master's Thesis Award, Taiwan Institute for Sustainable Energy. 2023. (Research Award)
  • (2) Po-Hsiang Wang. "PhD Student Discovery Award." Department of Chemical Engineering & Applied Chemistry, University of Toronto. 2018. (Research Award)